Due to the complexity of musical audio, real-time generation of MIDI is an experimental art-form.  

AudioExplorer offers a many options for note detection and MIDI generation, both in interactive and real-time (playback and record) modes.

 

Optionally emits MIDI to a selected MIDI port during real-time audio playback/record or as MIDI playback.
Offers a rich set of options for MIDI filtering and timing adjustment.
Generates MIDI in real-time and interactive modes.
Offers a rich set of options for MIDI filtering and timing adjustment.